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Posts Tagged ‘Hepatitis

COLORADO: “Bills to Protect Patients Move”

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Denver Daily News     (05.05.10)

Two bills intended to protect patients from dangerous health care workers have advanced in the Colorado Legislature. The measures – by Reps. Debbie Benefield (D-Arvada/Westminster) and Sara Gagliardi (D-Arvada) – were filed in response to the case of Kristen Diane Parker, a surgical technician whose drug-theft and needle-swap scheme potentially exposed thousands of patients to her hepatitis C infection. Parker is now serving a 30-year prison sentence. The bills seek to help medical facilities avoid hiring surgical technicians with a criminal background or a history of jeopardizing patient safety. HB 1414 passed the House and advances to the Senate; HB 1415 passed the House Tuesday in an initial voice vote.

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Written by pkids

May 6, 2010 at 11:14 pm

CALIFORNIA: “In Ads, Plea for Asians to Get Tested for Hepatitis”

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New York Times     (05.03.10):: Jesse McKinley

A new TV and print advertising campaign promoting hepatitis B vaccination debuts in San Francisco this week. The goal of the San Francisco Hep B Free-sponsored effort is to spur the city’s Asian-American population into action against the disease. The ads encourage residents to get a “simple blood test” because “hepatitis B can be treated, even prevented.”

City health officials report as many as one in 10 residents of Asian descent are infected with hepatitis B – one reason behind the city’s liver cancer rate, which is the nation’s highest. By comparison, the hepatitis B rate in the general population is roughly 1 in 1,000.

Central to the problem is the stigma attached to hepatitis B, which is endemic in most regions of Asia, say leaders of San Francisco’s Chinese-American community, the largest Asian ethnicity there.

According to Hep B Free committee member Ted Fang, the infection rate among Asian-Americans is particularly vexing considering a vaccine to prevent hepatitis B has been available for nearly 30 years. “We have the medical tools, so long as doctors will test their patients and monitor them,” he said.

A previous, less blunt campaign by the group did not go far enough, said Vicky M. Wong, president and chief executive of DAE, the San Francisco firm that worked with Hep B Free on the new campaign. “Saying ‘Life is beautiful; get tested,’ doesn’t work,” she said. The new ads show a range of Asian community members and ask the stark question, “Which one deserves to die?”

Though the ads are being published in languages including Chinese, Korean, and Vietnamese, a major target audience is English-speaking doctors outside the Asian community. These physicians may not be aware of the virus’ disproportionate impact on Asian-Americans, organizers say.

Written by pkids

May 6, 2010 at 10:48 pm

Posted in Hepatitis

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AMEDEO Hepatitis News 01/19/2010

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1. RALLON NI, Naggie S, Benito JM, Medrano J, et al.
Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients.
AIDS. 2010.
http://amedeo.com/p2.php?id=20389235&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

2. PAGE EE, Cox A, Atkins M, Nelson MR, et al.
Clearance of hepatitis C virus RNA from serum in HIV/hepatitis C virus coinfection indicates eradication from peripheral blood mononuclear cells.
AIDS. 2010.
http://amedeo.com/p2.php?id=20386424&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

3. BALART LA, Lisker-Melman M, Hamzeh FM, Kwok A, et al.
Peginterferon alpha-2a Plus Ribavirin in Latino and Non-Latino Whites With HCV Genotype 1: Histologic Outcomes and Tolerability From the LATINO Study.
Am J Gastroenterol. 2010.
http://amedeo.com/p2.php?id=20389293&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

4. DAVILA JA.
Diabetes and hepatocellular carcinoma: what role does diabetes have in the presence of other known risk factors?
Am J Gastroenterol. 2010;105:632-4.
http://amedeo.com/p2.php?id=20203644&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

5. REIJNDERS JG, Perquin MJ, Zhang N, Hansen BE, et al.
Nucleos(t)ide Analogues Only Induce Temporary Hepatitis B e Antigen Seroconversion in Most Patients with Chronic Hepatitis B.
Gastroenterology. 2010.
http://amedeo.com/p2.php?id=20381492&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

6. SHOUVAL D.
The impact of ribavirin treatment on spermatogenesis in patients with chronic hepatitis C.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20392511&s=hep&pm=55fdd48ca73ce1a

7. PAWLOTSKY JM.
More sensitive hepatitis C virus RNA detection: What for?
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20385426&s=hep&pm=55fdd48ca73ce1a

8. SARRAZIN C, Shiffman ML, Hadziyannis SJ, Lin A, et al.
Definition of rapid virologic response with a highly sensitive real-time
PCR-based HCV RNA assay in peginterferon alfa-2a plus ribavirin
response-guided therapy.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20385421&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

Written by pkids

April 16, 2010 at 9:42 pm

Report: Needle Exchange Program Helping Many and Should Continue

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Star-Ledger (Newark)     (04.09.10)

New Jersey’s pilot syringe access programs provide many public health benefits, without raising crime rates, according to an interim review. Seventy-eight percent of SAP clients said they hoped to avoid infections and needle-sharing. The state Department of Health and Senior Services commissioned the University of Medicine and Dentistry of New Jersey to conduct the evaluation, which was mandated by law.

In 2006, New Jersey authorized pilot SAPs for up to six municipalities, and five cities currently host sites. The programs are not state-funded but run by private community agencies.

The SAPs enrolled 4,482 IDUs, and an additional 1,324 non-SAP IDUs received clean injection supplies through secondary exchangers. The sites collected 295,736 used syringes and gave clients 706,568 sterile ones.

Of the SAP clients, 998 were successfully enrolled in drug treatment, representing 49 percent of all referrals for treatment under the Division of Addiction Services’ Needle Exchange Treatment Initiative. In fact, 10 percent of clients saw SAP participation as a first step to becoming drug-free, the report notes. In Newark’s SAP, operated by the New Jersey Community Research Initiative, 25 percent of some 1,250 clients have been admitted to treatment programs, said Bob Baxter, an institute director.

Many IV drug users (IDUs) are young adults. In Atlantic City’s SAP, people ages 18-25 represented 24 percent of all clients; this age group accounted for 19.5 percent of Camden SAP enrollees. Those proportions were “higher than expected,” the report said. Nationally, rates of hepatitis C virus infection are four times higher than HIV rates among young IDUs, the report said, noting that after five years of injecting, up to 90 percent of IDUs become HCV-infected.

A final report is due in January. The interim review, which includes recommendations to continue SAPs and increase outreach, can be viewed at http://www.state.nj.us/health/aids/documents/nj_sep_evaluation.pdf.

Written by pkids

April 14, 2010 at 10:00 pm

AMEDEO Hepatitis News 04/12/2010

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1. GUZZO C, Hopman WM, Mat NF, Wobeser W, et al.
Impact of HIV infection, highly active antiretroviral therapy, and hepatitis C coinfection on serum interleukin-27.
AIDS. 2010.
http://amedeo.com/p2.php?id=20375875&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

2. SINGH H, Thomas EJ, Sittig DF, Wilson L, et al.
Notification of abnormal lab test results in an electronic medical record:
do any safety concerns remain?
Am J Med. 2010;123:238-44.
http://amedeo.com/p2.php?id=20193832&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

3. NUNES J, Marinho RT, Velosa J.
A Post-cure Complication.
Am J Med. 2010;123:223-4.
http://amedeo.com/p2.php?id=20193828&s=hep&pm=55fdd48ca73ce1a

4. MUNOZ BERTRAN E, Perez Ceballos E, Gomez Espin R, Ortega Gonzalez I, et al.
[Hepatitis B reactivation in an HbsAg-negative/anti-HBc-positive patient with B-cell non-Hodgkin lymphoma receiving chemotherapy with rituximab.] Gastroenterol Hepatol. 2010.
http://amedeo.com/p2.php?id=20363054&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

5. PFEFFER S, Baumert TF.
Antagonizing microRNA-122 and treatment of hepatitis C virus infection.
Hepatology. 2010;51:1461-3.
http://amedeo.com/p2.php?id=20373371&s=hep&pm=55fdd48ca73ce1a

6. SINGAL AK, Anand BS.
Tailoring Treatment Duration to 12 to 16 Weeks in Hepatitis C Genotype 2 or
3 With Rapid Virologic Response: Systematic Review and Metaanalysis of Randomized Controlled Trials.
J Clin Gastroenterol. 2010.
http://amedeo.com/p2.php?id=20375729&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

7. MCHUTCHISON JG, Manns MP, Muir AJ, Terrault NA, et al.
Telaprevir for previously treated chronic HCV infection.
N Engl J Med. 2010;362:1292-303.
http://amedeo.com/p2.php?id=20375406&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

8. GELSON W, Hoare M, Unitt E, Palmer C, et al.
Heterogeneous inflammatory changes in liver graft recipients with normal biochemistry.
Transplantation. 2010;89:739-48.
http://amedeo.com/p2.php?id=20134396&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

9. DI BENEDETTO F, Di Sandro S, De Ruvo N, Montalti R, et al.
First Report on a Series of HIV Patients Undergoing Rapamycin Monotherapy
After Liver Transplantation.
Transplantation. 2009.
http://amedeo.com/p2.php?id=20048692&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

10. ALAVIAN SM, Tabatabaei SV.
The effect of diabetes mellitus on immunological response to hepatitis B
virus vaccine in individuals with chronic kidney disease: A meta-analysis of
current literature.
Vaccine. 2010.
http://amedeo.com/p2.php?id=20371390&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

11. BAYARD F, Malmassari S, Deng Q, Lone YC, et al.
Hepatitis B virus (HBV)-derived DRB1*0101-restricted CD4 T-cell epitopes
help in the development of HBV-specific CD8+ T cells in vivo.
Vaccine. 2010.
http://amedeo.com/p2.php?id=20362206&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

Written by pkids

April 9, 2010 at 5:48 pm

AMEDEO Hepatitis News 04/05/2010

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1. MELIN P, Chousterman M, Fontanges T, Ouzan D, et al.
Effectiveness of chronic hepatitis C treatment in drug users in routine clinical
practice: results of a prospective cohort study.
Eur J Gastroenterol Hepatol. 2010.
http://amedeo.com/p2.php?id=20351554&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

2. GUTELIUS B, Perz JF, Parker MM, Hallack R, et al.
Multiple Clusters of Hepatitis Virus Infections Associated with Anesthesia for Outpatient Endoscopy Procedures.
Gastroenterology. 2010.
http://amedeo.com/p2.php?id=20353790&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

3. DUREJA P, Lucey MR.
The place of liver transplantation in the treatment of severe alcoholic hepatitis.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20347501&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

4. GENTILE I, Borgia G.
Surrogate endpoints and non-inferiority trials in chronic viral hepatitis.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20347500&s=hep&pm=55fdd48ca73ce1a

5. CLEMENT S, Pascarella S, Conzelmann S, Gonelle-Gispert C, et al.
The hepatitis C virus core protein indirectly induces alpha-smooth muscle actin expression in hepatic stellate cells via interleukin-8.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20347177&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

6. CARDOSO AC, Moucari R, Figueiredo-Mendes C, Ripault MP, et al.
Impact of peginterferon and ribavirin therapy on hepatocellular carcinoma:
Incidence and survival in hepatitis C patients with advanced fibrosis.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20346533&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

7. FUKUHARA T, Taketomi A, Okano S, Ikegami T, et al.
Mutations in hepatitis C virus genotype 1b and the sensitivity of
interferon-ribavirin therapy after liver transplantation.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20346532&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

8. SCHAPER M, Rodriguez-Frias F, Jardi R, Tabernero D, et al.
Quantitative longitudinal evaluations of hepatitis delta virus RNA and
hepatitis B virus DNA shows a dynamic, complex replicative profile in chronic
hepatitis B and D.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20346531&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

9. BEAUVILLAIN C, Meloni F, Sirard JC, Blanchard S, et al.
The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the
recognition of the hepatitis C virus non-structural protein 3 by dendritic cells.
J Hepatol. 2010.
http://amedeo.com/p2.php?id=20338659&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

10. BUKH J, Meuleman P, Tellier R, Engle RE, et al.
Challenge Pools of Hepatitis C Virus Genotypes 1-6 Prototype Strains:
Replication Fitness and Pathogenicity in Chimpanzees
and Human Liver-Chimeric MouseModels.
J Infect Dis. 2010.
http://amedeo.com/p2.php?id=20353362&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

11. MEHTA N, Cunningham CK, Flynn P, Pepe J, et al.
Impaired generation of hepatitis B virus-specific memory B cells in HIV
infected individuals following vaccination.
Vaccine. 2010.
http://amedeo.com/p2.php?id=20356567&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

12. NIEDERAU C, Bemba G, Kautz A, Bertram T, et al.
[Waiting time for and length of physicianc’s consultation define the
patient-physician interaction: results of a prospective study in 478
patients with chronic viral hepatitis]
Z Gastroenterol. 2010;48:455-64.
http://amedeo.com/p2.php?id=20352592&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

Written by pkids

April 2, 2010 at 5:35 pm

AMEDEO Hepatitis Articles 03/22/2010

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1. KHATTAB M, Eslam M, Sharwae MA, Shatat M, et al.
Insulin Resistance Predicts Rapid Virologic Response to Peginterferon/Ribavirin Combination Therapy in Hepatitis C Genotype 4 Patients.
Am J Gastroenterol. 2010.
http://amedeo.com/p2.php?id=20234345&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

2. LEWIS-XIMENEZ LL, Lauer GM, Schulze Zur Wiesch J, de Sousa PS, et al.
Prospective Follow-Up of Patients with Acute Hepatitis C Virus Infection in Brazil.
Clin Infect Dis. 2010.
http://amedeo.com/p2.php?id=20235831&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

3. GIANNOUSIS IP, Papatheodoridis GV, Deutsch MJ, Manolakopoulos SG, et al.
The burden and recent epidemiological changes of the main chronic liver diseases in a Greek referral tertiary centre.
Eur J Gastroenterol Hepatol. 2010;22:172-9.
http://amedeo.com/p2.php?id=19738477&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

4. LIN W, Tsai WL, Shao RX, Wu G, et al.
HCV regulates TGF-beta1 production through the generation of reactive oxygen
species in an NFkappaB-dependent manner.
Gastroenterology. 2010.
http://amedeo.com/p2.php?id=20230822&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

5. ZEUZEM S.
Do differences in pegylation of interferon alfa matter?
Gastroenterology. 2010;138:34-6.
http://amedeo.com/p2.php?id=19932662&s=hep&pm=55fdd48ca73ce1a

6. SUBRAMANIAN A, Sulkowski M, Barin B, Stablein D, et al.
MELD score is an important predictor of pretransplantation mortality in
HIV-infected liver transplant candidates.
Gastroenterology. 2010;138:159-64.
http://amedeo.com/p2.php?id=19800334&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

7. KLUWE J, Pradere JP, Gwak GY, Mencin A, et al.
Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition.
Gastroenterology. 2009.
http://amedeo.com/p2.php?id=19782079&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

8. LI JH, Qian Lao X, Tillmann HL, Rowell J, et al.
Interferon-lambda genotype and low serum low-density lipoprotein cholesterol
levels in patients with chronic hepatitis C infection.
Hepatology. 2010.
http://amedeo.com/p2.php?id=20235331&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

9. KENDRICK SF, O’Boyle G, Mann J, Zeybel M, et al.
Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis.
Hepatology. 2010.
http://amedeo.com/p2.php?id=20232292&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

10. BONKOVSKY HL, Lambrecht RW, Naishadham D.
Genetic variations in heme oxygenase-1 and chronic hepatitis.
Hepatology. 2010.
http://amedeo.com/p2.php?id=20232486&s=hep&pm=55fdd48ca73ce1a

11. LAPIERRE P, Beland K, Martin C, Alvarez F Jr, et al.
Forkhead box p3(+) regulatory T cell underlies male resistance to
experimental type 2 autoimmune hepatitis.
Hepatology. 2010.
http://amedeo.com/p2.php?id=20232291&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

12. HALFON P, Martinot-Peignoux M, Khiri H, Marcellin P, et al.
Quantification of genotype 4 serum samples: Impact of hepatitis C virus
genetic variability.
Hepatology. 2010.
http://amedeo.com/p2.php?id=20229587&s=hep&pm=55fdd48ca73ce1a

13. MOLINA-JIMENEZ F, Benedicto I, Murata M, Martin-Vilchez S, et al.
Expression of pituitary tumor-transforming gene 1 (PTTG1)/securin in
hepatitis B virus (HBV)-associated liver diseases: Evidence for an HBV X
protein-mediated inhibition of PTTG1 ubiquitination and degradation.
Hepatology. 2010;51:777-87.
http://amedeo.com/p2.php?id=20198633&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

14. BEN ALAYA BN, Bahri O, Chlif S, Bettaieb J, et al.
Heterogeneity of hepatitis B transmission in Tunisia: Risk factors for
infection and chronic carriage before the introduction of a universal vaccine program.
Vaccine. 2010.
http://amedeo.com/p2.php?id=20226251&s=hep&pm=55fdd48ca73ce1a
ABSTRACT available

Written by pkids

March 22, 2010 at 10:33 pm